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Wnt5a induces ROR1 to complex with HS1 to enhance migration of chronic lymphocytic leukemia cells

ROR1 (receptor tyrosine kinase-like orphan receptor 1) is a conserved, oncoembryonic surface antigen expressed in chronic lymphocytic leukemia (CLL). We found that ROR1 associates with hematopoietic-lineage-cell-specific protein 1 (HS1) in freshly isolated CLL cells or in CLL cells cultured with exo...

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Detalles Bibliográficos
Autores principales: Hasan, M K, Yu, J, Chen, L, Cui, Bing, Widhopf II, G F, Rassenti, L, Shen, Z, Briggs, S P, Kipps, T J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670028/
https://www.ncbi.nlm.nih.gov/pubmed/28465529
http://dx.doi.org/10.1038/leu.2017.133