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Chemokine Signaling during Midline Epithelial Seam Disintegration Facilitates Palatal Fusion

Disintegration of the midline epithelial seam (MES) is crucial for palatal fusion, and failure results in cleft palate. Palatal fusion and wound repair share many common signaling pathways related to epithelial-mesenchymal cross-talk. We postulate that chemokine CXCL11, its receptor CXCR3, and the c...

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Detalles Bibliográficos
Autores principales: Suttorp, Christiaan M., Cremers, Niels A., van Rheden, René, Regan, Raymond F., Helmich, Pia, van Kempen, Sven, Kuijpers-Jagtman, Anne M., Wagener, Frank A.D.T.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670099/
https://www.ncbi.nlm.nih.gov/pubmed/29164113
http://dx.doi.org/10.3389/fcell.2017.00094