Dense and accurate whole-chromosome haplotyping of individual genomes

The diploid nature of the human genome is neglected in many analyses done today, where a genome is perceived as a set of unphased variants with respect to a reference genome. This lack of haplotype-level analyses can be explained by a lack of methods that can produce dense and accurate chromosome-le...

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Detalles Bibliográficos
Autores principales: Porubsky, David, Garg, Shilpa, Sanders, Ashley D., Korbel, Jan O., Guryev, Victor, Lansdorp, Peter M., Marschall, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670131/
https://www.ncbi.nlm.nih.gov/pubmed/29101320
http://dx.doi.org/10.1038/s41467-017-01389-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670131/
https://www.ncbi.nlm.nih.gov/pubmed/29101320
http://dx.doi.org/10.1038/s41467-017-01389-4

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