T cells upon activation promote endothelin 1 production in monocytes via IFN-γ and TNF-α

Endothelin 1 (ET-1), mainly produced from vascular endothelial cells, induces vasoconstriction in physiological conditions. The endothelin receptor antagonist is among the most effective agents for pulmonary hypertension. However, little is known about the production source of ET-1 in inflammation a...

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Detalles Bibliográficos
Autores principales: Shinagawa, Shoshi, Okazaki, Takahiro, Ikeda, Mari, Yudoh, Kazuo, Kisanuki, Yaz Y., Yanagisawa, Masashi, Kawahata, Kimito, Ozaki, Shoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670167/
https://www.ncbi.nlm.nih.gov/pubmed/29101349
http://dx.doi.org/10.1038/s41598-017-14202-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670167/
https://www.ncbi.nlm.nih.gov/pubmed/29101349
http://dx.doi.org/10.1038/s41598-017-14202-5

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