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Plasmodium DNA-mediated TLR9 activation of T-bet(+) B cells contributes to autoimmune anaemia during malaria

Infectious pathogens contribute to the development of autoimmune disorders, but the mechanisms connecting these processes are incompletely understood. Here we show that Plasmodium DNA induces autoreactive responses against erythrocytes by activating a population of B cells expressing CD11c and the t...

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書目詳細資料
Autores principales: Rivera-Correa, J., Guthmiller, J. J., Vijay, R., Fernandez-Arias, C., Pardo-Ruge, M. A., Gonzalez, S., Butler, N. S., Rodriguez, A.
格式: Online Artículo Texto
語言:English
出版: Nature Publishing Group UK 2017
主題:
在線閱讀:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670202/
https://www.ncbi.nlm.nih.gov/pubmed/29101363
http://dx.doi.org/10.1038/s41467-017-01476-6