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Plasmodium DNA-mediated TLR9 activation of T-bet(+) B cells contributes to autoimmune anaemia during malaria

Infectious pathogens contribute to the development of autoimmune disorders, but the mechanisms connecting these processes are incompletely understood. Here we show that Plasmodium DNA induces autoreactive responses against erythrocytes by activating a population of B cells expressing CD11c and the t...

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Detalles Bibliográficos
Autores principales: Rivera-Correa, J., Guthmiller, J. J., Vijay, R., Fernandez-Arias, C., Pardo-Ruge, M. A., Gonzalez, S., Butler, N. S., Rodriguez, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670202/
https://www.ncbi.nlm.nih.gov/pubmed/29101363
http://dx.doi.org/10.1038/s41467-017-01476-6