Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis

Genomic alterations driving tumorigenesis result from the interaction of environmental exposures and endogenous cellular processes. With a diversity of risk factors, liver cancer is an ideal model to study these interactions. Here, we analyze the whole genomes of 44 new and 264 published liver cance...

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Detalles Bibliográficos
Autores principales: Letouzé, Eric, Shinde, Jayendra, Renault, Victor, Couchy, Gabrielle, Blanc, Jean-Frédéric, Tubacher, Emmanuel, Bayard, Quentin, Bacq, Delphine, Meyer, Vincent, Semhoun, Jérémy, Bioulac-Sage, Paulette, Prévôt, Sophie, Azoulay, Daniel, Paradis, Valérie, Imbeaud, Sandrine, Deleuze, Jean-François, Zucman-Rossi, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670220/
https://www.ncbi.nlm.nih.gov/pubmed/29101368
http://dx.doi.org/10.1038/s41467-017-01358-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670220/
https://www.ncbi.nlm.nih.gov/pubmed/29101368
http://dx.doi.org/10.1038/s41467-017-01358-x

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