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Identification of an analgesic lipopeptide produced by the probiotic Escherichia coli strain Nissle 1917

Administration of the probiotic Escherichia coli strain Nissle 1917 (EcN) decreases visceral pain associated with irritable bowel syndrome. Mutation of clbA, a gene involved in the biosynthesis of secondary metabolites, including colibactin, was previously shown to abrogate EcN probiotic activity. H...

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Detalles Bibliográficos
Autores principales: Pérez-Berezo, Teresa, Pujo, Julien, Martin, Patricia, Le Faouder, Pauline, Galano, Jean-Marie, Guy, Alexandre, Knauf, Claude, Tabet, Jean Claude, Tronnet, Sophie, Barreau, Frederick, Heuillet, Maud, Dietrich, Gilles, Bertrand-Michel, Justine, Durand, Thierry, Oswald, Eric, Cenac, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670229/
https://www.ncbi.nlm.nih.gov/pubmed/29101366
http://dx.doi.org/10.1038/s41467-017-01403-9