MicroRNA-27a regulates hepatic lipid metabolism and alleviates NAFLD via repressing FAS and SCD1

MicroRNAs are implicated as crucial mediators in metabolic diseases including obesity, diabetes, and non-alcoholic fatty liver diseases (NAFLD). Here, we show miR-27a attenuated hepatic de novo lipogenesis and alleviated obesity-initiated NAFLD through inhibiting Fasn and Scd1 in liver. Hepatic leve...

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Detalles Bibliográficos
Autores principales: Zhang, Meiyuan, Sun, Weilan, Zhou, Minghao, Tang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670231/
https://www.ncbi.nlm.nih.gov/pubmed/29101357
http://dx.doi.org/10.1038/s41598-017-15141-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670231/
https://www.ncbi.nlm.nih.gov/pubmed/29101357
http://dx.doi.org/10.1038/s41598-017-15141-x

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