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piRNAs and Aubergine cooperate with Wispy poly(A) polymerase to stabilize mRNAs in the germ plasm

Piwi-interacting RNAs (piRNAs) and PIWI proteins play a crucial role in germ cells by repressing transposable elements and regulating gene expression. In Drosophila, maternal piRNAs are loaded into the embryo mostly bound to the PIWI protein Aubergine (Aub). Aub targets maternal mRNAs through incomp...

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Detalles Bibliográficos
Autores principales: Dufourt, Jérémy, Bontonou, Gwénaëlle, Chartier, Aymeric, Jahan, Camille, Meunier, Anne-Cécile, Pierson, Stéphanie, Harrison, Paul F., Papin, Catherine, Beilharz, Traude H., Simonelig, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670238/
https://www.ncbi.nlm.nih.gov/pubmed/29101389
http://dx.doi.org/10.1038/s41467-017-01431-5