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Targeting deubiquitinating enzymes in cancer stem cells

Cancer stem cells (CSCs) are rare but accounted for tumor initiation, progression, metastasis, relapse and therapeutic resistance. Ubiquitination and deubiquitination of stemness-related proteins are essential for CSC maintenance and differentiation, even leading to execute various stem cell fate ch...

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Detalles Bibliográficos
Autores principales: Lei, Hu, Shan, Huizhuang, Wu, Yingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670729/
https://www.ncbi.nlm.nih.gov/pubmed/29142505
http://dx.doi.org/10.1186/s12935-017-0472-0