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Synchronicity and Rhythmicity of Purkinje Cell Firing during Generalized Spike-and-Wave Discharges in a Natural Mouse Model of Absence Epilepsy

Absence epilepsy is characterized by the occurrence of generalized spike and wave discharges (GSWDs) in electrocorticographical (ECoG) recordings representing oscillatory activity in thalamocortical networks. The oscillatory nature of GSWDs has been shown to be reflected in the simple spike activity...

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Detalles Bibliográficos
Autores principales: Kros, Lieke, Lindeman, Sander, Eelkman Rooda, Oscar H. J., Murugesan, Pavithra, Bina, Lorenzo, Bosman, Laurens W. J., De Zeeuw, Chris I., Hoebeek, Freek E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671558/
https://www.ncbi.nlm.nih.gov/pubmed/29163057
http://dx.doi.org/10.3389/fncel.2017.00346