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Tagging of Endogenous BK Channels with a Fluorogen-Activating Peptide Reveals β4-Mediated Control of Channel Clustering in Cerebellum

BK channels are critical regulators of neuronal activity, controlling firing, neurotransmitter release, cerebellar function, and BK channel mutations have been linked to seizure disorders. Modulation of BK channel gating is well characterized, regulated by accessory subunit interactions, intracellul...

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Detalles Bibliográficos
Autores principales: Pratt, Christopher P., Kuljis, Dika A., Homanics, Gregg E., He, Jianjun, Kolodieznyi, Dmytro, Dudem, Srikanth, Hollywood, Mark A., Barth, Alison L., Bruchez, Marcel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671578/
https://www.ncbi.nlm.nih.gov/pubmed/29163049
http://dx.doi.org/10.3389/fncel.2017.00337