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Tagging of Endogenous BK Channels with a Fluorogen-Activating Peptide Reveals β4-Mediated Control of Channel Clustering in Cerebellum
BK channels are critical regulators of neuronal activity, controlling firing, neurotransmitter release, cerebellar function, and BK channel mutations have been linked to seizure disorders. Modulation of BK channel gating is well characterized, regulated by accessory subunit interactions, intracellul...
Autores principales: | Pratt, Christopher P., Kuljis, Dika A., Homanics, Gregg E., He, Jianjun, Kolodieznyi, Dmytro, Dudem, Srikanth, Hollywood, Mark A., Barth, Alison L., Bruchez, Marcel P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671578/ https://www.ncbi.nlm.nih.gov/pubmed/29163049 http://dx.doi.org/10.3389/fncel.2017.00337 |
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