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Potential implications of practice effects in Alzheimer's disease prevention trials
INTRODUCTION: Practice effects (PEs) present a potential confound in clinical trials with cognitive outcomes. A single-blind placebo run-in design, with repeated cognitive outcome assessments before randomization to treatment, can minimize effects of practice on trial outcome. METHODS: We investigat...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671629/ https://www.ncbi.nlm.nih.gov/pubmed/29124111 http://dx.doi.org/10.1016/j.trci.2017.08.010 |