Cargando…

Targeting Dengue Virus NS-3 Helicase by Ligand based Pharmacophore Modeling and Structure based Virtual Screening

Dengue fever is an emerging public health concern, with several million viral infections occur annually, for which no effective therapy currently exist. Non-structural protein 3 (NS-3) Helicase encoded by the dengue virus (DENV) is considered as a potential drug target to design new and effective dr...

Descripción completa

Detalles Bibliográficos
Autores principales: Halim, Sobia A., Khan, Shanza, Khan, Ajmal, Wadood, Abdul, Mabood, Fazal, Hussain, Javid, Al-Harrasi, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671650/
https://www.ncbi.nlm.nih.gov/pubmed/29164104
http://dx.doi.org/10.3389/fchem.2017.00088