Small Molecule Supplements Improve Cultured Megakaryocyte Polyploidization by Modulating Multiple Cell Cycle Regulators

Platelets (PLTs) are produced by megakaryocytes (MKs) that completed differentiation and endomitosis. Endomitosis is an important process in which the cell replicates its DNA without cytokinesis and develops highly polyploid MK. In this study, to gain a better PLTs production, four small molecules (...

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Detalles Bibliográficos
Autores principales: Zou, Xiaojing, Qu, Mingyi, Fang, Fang, Fan, Zeng, Chen, Lin, Yue, Wen, Xie, Xiaoyan, Pei, Xuetao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671672/
https://www.ncbi.nlm.nih.gov/pubmed/29201898
http://dx.doi.org/10.1155/2017/2320519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671672/
https://www.ncbi.nlm.nih.gov/pubmed/29201898
http://dx.doi.org/10.1155/2017/2320519

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