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Selective and Irreversible Induction of Necroptotic Cell Death in Lung Tumorspheres by Short-Term Exposure to Verapamil in Combination with Sorafenib

The presence of highly resistant cancer cells and the toxicity to normal cells are key factors that limit chemotherapy. Here, we used two models of highly resistant lung cancer cells: (1) adherent cells growing under prolonged periods of serum starvation (PPSS) and (2) cells growing as floating tumo...

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Detalles Bibliográficos
Autores principales: Yakisich, Juan Sebastian, Kulkarni, Yogesh, Azad, Neelam, Iyer, Anand Krishnan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671752/
https://www.ncbi.nlm.nih.gov/pubmed/29201061
http://dx.doi.org/10.1155/2017/5987015