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KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition

Cell cycle dysregulation leads to uncontrolled cell proliferation and tumorigenesis. Understanding the molecular mechanisms underlying cell cycle progression can provide clues leading to the identification of key proteins involved in cancer development. In this study, we performed proteomics analysi...

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Detalles Bibliográficos
Autores principales: Zhong, Y, Yang, J, Xu, W W, Wang, Y, Zheng, C-C, Li, B, He, Q-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671937/
https://www.ncbi.nlm.nih.gov/pubmed/28869606
http://dx.doi.org/10.1038/onc.2017.287