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Pre-45s rRNA promotes colon cancer and is associated with poor survival of CRC patients

One characteristic of cancer cells is the abnormally high rate of cell metabolism to sustain their enhanced proliferation. However, the behind mechanism of this phenomenon is still elusive. Here we find that enhanced precursor 45s ribosomal RNA (pre-45s rRNA) is one of the core mechanisms in promoti...

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Detalles Bibliográficos
Autores principales: Tsoi, H, Lam, K C, Dong, Y, Zhang, X, Lee, C K, Zhang, J, Ng, S C, Ng, S S M, Zheng, S, Chen, Y, Fang, J, Yu, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671943/
https://www.ncbi.nlm.nih.gov/pubmed/28692053
http://dx.doi.org/10.1038/onc.2017.86