FOXO3-mediated chemo-protection in high-stage neuroblastoma depends on wild-type TP53 and SESN3

Forkhead box O class transcription factors are homeostasis regulators that control cell death, longevity and therapy-resistance. In neuroblastoma (NB), nuclear FOXO3 correlates with stage M disease and poor prognosis. To analyze whether FOXO3 contributes to drug-resistance in this childhood cancer,...

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Detalles Bibliográficos
Autores principales: Rupp, M, Hagenbuchner, J, Rass, B, Fiegl, H, Kiechl-Kohlendorfer, U, Obexer, P, Ausserlechner, M J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671944/
https://www.ncbi.nlm.nih.gov/pubmed/28869600
http://dx.doi.org/10.1038/onc.2017.288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671944/
https://www.ncbi.nlm.nih.gov/pubmed/28869600
http://dx.doi.org/10.1038/onc.2017.288

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