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Evidence Suggesting Absence of Mitochondrial DNA Methylation

Methylation of nuclear genes encoding mitochondrial proteins participates in the regulation of mitochondria function. The existence of cytosine methylation in the mitochondrial genome is debated. To investigate whether mitochondrial DNA (mtDNA) is methylated, we used both targeted- and whole mitocho...

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Detalles Bibliográficos
Autores principales: Mechta, Mie, Ingerslev, Lars R., Fabre, Odile, Picard, Martin, Barrès, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671948/
https://www.ncbi.nlm.nih.gov/pubmed/29163634
http://dx.doi.org/10.3389/fgene.2017.00166