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MicroRNA-4443 Causes CD4+ T Cells Dysfunction by Targeting TNFR-Associated Factor 4 in Graves’ Disease

CONTEXT: Aberrant CD4+ T cell function plays a critical role in the process of Graves’ disease (GD). MicroRNAs (miRNAs) are important regulators of T cell activation, proliferation, and cytokine production. However, the contribution of miRNAs to CD4+ T cell dysfunction in GD remains unclear. OBJECTI...

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Detalles Bibliográficos
Autores principales: Qi, Yicheng, Zhou, Yulin, Chen, Xinxin, Ye, Lei, Zhang, Qianwei, Huang, Fengjiao, Cui, Bin, Lin, Dongping, Ning, Guang, Wang, Weiqing, Wang, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671953/
https://www.ncbi.nlm.nih.gov/pubmed/29163513
http://dx.doi.org/10.3389/fimmu.2017.01440