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Adoptive cell therapy with CD4(+) T helper 1 cells and CD8(+) cytotoxic T cells enhances complete rejection of an established tumour, leading to generation of endogenous memory responses to non-targeted tumour epitopes

The results of adoptive T-cell therapies (ACTs) are very encouraging and show clinical evidence that ACT can provide a cure for patients with metastatic disease. However, various response rates and long-term cancer remission have been observed in different ACT trials. The types of T cells, prior tre...

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Detalles Bibliográficos
Autores principales: Li, Kunyu, Donaldson, Braeden, Young, Vivienne, Ward, Vernon, Jackson, Christopher, Baird, Margaret, Young, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671987/
https://www.ncbi.nlm.nih.gov/pubmed/29114389
http://dx.doi.org/10.1038/cti.2017.37