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Adoptive cell therapy with CD4(+) T helper 1 cells and CD8(+) cytotoxic T cells enhances complete rejection of an established tumour, leading to generation of endogenous memory responses to non-targeted tumour epitopes
The results of adoptive T-cell therapies (ACTs) are very encouraging and show clinical evidence that ACT can provide a cure for patients with metastatic disease. However, various response rates and long-term cancer remission have been observed in different ACT trials. The types of T cells, prior tre...
Autores principales: | Li, Kunyu, Donaldson, Braeden, Young, Vivienne, Ward, Vernon, Jackson, Christopher, Baird, Margaret, Young, Sarah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671987/ https://www.ncbi.nlm.nih.gov/pubmed/29114389 http://dx.doi.org/10.1038/cti.2017.37 |
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