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Attenuation of miR-34a protects cardiomyocytes against hypoxic stress through maintenance of glycolysis

MiRNAs are a class of endogenous, short, single-stranded, non-coding RNAs, which are tightly linked to cardiac disorders such as myocardial ischemia/reperfusion (I/R) injury. MiR-34a is known to be involved in the hypoxia-induced cardiomyocytes apoptosis. However, the molecular mechanisms are unclea...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Liu, Gang, Gao, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672082/
https://www.ncbi.nlm.nih.gov/pubmed/28894025
http://dx.doi.org/10.1042/BSR20170925