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TET1 exerts its tumour suppressor function by regulating autophagy in glioma cells

DNA methylation and demethylation play a critical role in the regulation of the molecular pathogenesis of gliomas. Tet methylcytosine dioxygenase 1 (TET1) catalyses the sequential oxidation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine, (5hmC) leading to eventual DNA demethylation. It has bee...

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Detalles Bibliográficos
Autores principales: Fu, Rui, Ding, Yan, Luo, Jie, Yu, Li, Li, Cheng Lin, Li, Dong Sheng, Guo, Shi Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672083/
https://www.ncbi.nlm.nih.gov/pubmed/28341638
http://dx.doi.org/10.1042/BSR20160523