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An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases

The membrane of the endoplasmic reticulum (ER) of nucleated human cells harbors the protein translocon, which facilitates membrane integration or translocation of almost every newly synthesized polypeptide targeted to organelles of the endo- and exocytotic pathway. The translocon comprises the polyp...

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Detalles Bibliográficos
Autores principales: Lang, Sven, Pfeffer, Stefan, Lee, Po-Hsien, Cavalié, Adolfo, Helms, Volkhard, Förster, Friedrich, Zimmermann, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672155/
https://www.ncbi.nlm.nih.gov/pubmed/29163222
http://dx.doi.org/10.3389/fphys.2017.00887