A Pipeline for High-Throughput Concentration Response Modeling of Gene Expression for Toxicogenomics

Cell-based assays are an attractive option to measure gene expression response to exposure, but the cost of whole-transcriptome RNA sequencing has been a barrier to the use of gene expression profiling for in vitro toxicity screening. In addition, standard RNA sequencing adds variability due to vari...

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Detalles Bibliográficos
Autores principales: House, John S., Grimm, Fabian A., Jima, Dereje D., Zhou, Yi-Hui, Rusyn, Ivan, Wright, Fred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672545/
https://www.ncbi.nlm.nih.gov/pubmed/29163636
http://dx.doi.org/10.3389/fgene.2017.00168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672545/
https://www.ncbi.nlm.nih.gov/pubmed/29163636
http://dx.doi.org/10.3389/fgene.2017.00168

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