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A Pipeline for High-Throughput Concentration Response Modeling of Gene Expression for Toxicogenomics
Cell-based assays are an attractive option to measure gene expression response to exposure, but the cost of whole-transcriptome RNA sequencing has been a barrier to the use of gene expression profiling for in vitro toxicity screening. In addition, standard RNA sequencing adds variability due to vari...
Autores principales: | House, John S., Grimm, Fabian A., Jima, Dereje D., Zhou, Yi-Hui, Rusyn, Ivan, Wright, Fred A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672545/ https://www.ncbi.nlm.nih.gov/pubmed/29163636 http://dx.doi.org/10.3389/fgene.2017.00168 |
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