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α2δ-1 Signaling Drives Cell Death, Synaptogenesis, Circuit Reorganization, and Gabapentin-Mediated Neuroprotection in a Model of Insult-Induced Cortical Malformation

Developmental cortical malformations (DCMs) result from pre- and perinatal insults, as well as genetic mutations. Hypoxia, viral infection, and traumatic injury are the most common environmental causes of DCMs, and are associated with the subsyndromes focal polymicrogyria and focal cortical dysplasi...

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Detalles Bibliográficos
Autores principales: Lau, Lauren A., Noubary, Farzad, Wang, Dongqing, Dulla, Chris G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672548/
https://www.ncbi.nlm.nih.gov/pubmed/29109971
http://dx.doi.org/10.1523/ENEURO.0316-17.2017