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Glucose-regulated protein 75 determines ER–mitochondrial coupling and sensitivity to oxidative stress in neuronal cells

The crosstalk between different organelles allows for the exchange of proteins, lipids and ions. Endoplasmic reticulum (ER) and mitochondria are physically linked and signal through the mitochondria-associated membrane (MAM) to regulate the transfer of Ca(2+) from ER stores into the mitochondrial ma...

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Detalles Bibliográficos
Autores principales: Honrath, Birgit, Metz, Isabell, Bendridi, Nadia, Rieusset, Jennifer, Culmsee, Carsten, Dolga, Amalia M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672593/
https://www.ncbi.nlm.nih.gov/pubmed/29367884
http://dx.doi.org/10.1038/cddiscovery.2017.76