Determination of protonation states of iminosugar–enzyme complexes using photoinduced electron transfer

A series of N-alkylated analogues of 1-deoxynojirimycin containing a fluorescent 10-chloro-9-anthracene group in the N-alkyl substituent were prepared. The anthracene group acted as a reporting group for protonation at the nitrogen in the iminosugar because an unprotonated amine was found to quench...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Olsen, Jacob Ingemar, Laursen, Bo W., Navarro Poulsen, Jens Christian, Bols, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672842/
https://www.ncbi.nlm.nih.gov/pubmed/29163889
http://dx.doi.org/10.1039/c7sc01540b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672842/
https://www.ncbi.nlm.nih.gov/pubmed/29163889
http://dx.doi.org/10.1039/c7sc01540b

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