Kras(G12D) upregulates Notch signaling to induce gallbladder tumorigenesis in mice

BACKGROUND: Kras mutations and increased Notch activation occur frequently in gallbladder cancer. However, their roles in gallbladder carcinogenesis have not been defined. This study was aimed at determining whether expression of mutant Kras was sufficient to induce gallbladder carcinoma and whether...

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Detalles Bibliográficos
Autores principales: Chung, Wen-Cheng, Wang, Junqing, Zhou, Yunyun, Xu, Keli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672897/
https://www.ncbi.nlm.nih.gov/pubmed/29142904
http://dx.doi.org/10.18632/oncoscience.368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672897/
https://www.ncbi.nlm.nih.gov/pubmed/29142904
http://dx.doi.org/10.18632/oncoscience.368

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