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Randomized clinical trial: efficacy and safety of plecanatide in the treatment of chronic idiopathic constipation

BACKGROUND: Plecanatide, with the exception of a single amino acid replacement, is identical to human uroguanylin and is approved in the United States for adults with chronic idiopathic constipation (CIC). This double-blind, placebo-controlled, phase III study evaluated the efficacy and safety of pl...

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Detalles Bibliográficos
Autores principales: DeMicco, Michael, Barrow, Laura, Hickey, Bernadette, Shailubhai, Kunwar, Griffin, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673020/
https://www.ncbi.nlm.nih.gov/pubmed/29147135
http://dx.doi.org/10.1177/1756283X17734697