Salicylic acid metabolites and derivatives inhibit CDK activity: Novel insights into aspirin's chemopreventive effects against colorectal cancer

Aspirin's potential as a drug continues to be evaluated for the prevention of colorectal cancer (CRC). Although multiple targets for aspirin and its metabolite, salicylic acid, have been identified, no unifying mechanism has been proposed to clearly explain its chemopreventive effects. Our goal...

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Detalles Bibliográficos
Autores principales: Dachineni, Rakesh, Kumar, D. Ramesh, Callegari, Eduardo, Kesharwani, Siddharth S., Sankaranarayanan, Ranjini, Seefeldt, Teresa, Tummala, Hemachand, Bhat, G. Jayarama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673027/
https://www.ncbi.nlm.nih.gov/pubmed/29075787
http://dx.doi.org/10.3892/ijo.2017.4167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673027/
https://www.ncbi.nlm.nih.gov/pubmed/29075787
http://dx.doi.org/10.3892/ijo.2017.4167

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