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Prevalence of hepatitis C virus-resistant association substitutions to direct-acting antiviral agents in treatment-naïve hepatitis C genotype 1b-infected patients in western China

BACKGROUND: Direct-acting antivirals (DAAs) against hepatitis C virus (HCV) are potent and highly efficacious. However, resistance-associated substitutions (RASs) relevant to DAAs can impair treatment effectiveness even at baseline. Moreover, the prevalence of baseline RASs in HCV genotype 1b-infect...

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Detalles Bibliográficos
Autores principales: Li, Zhao, Chen, Zhi-wei, Li, Hu, Ren, Hong, Hu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673042/
https://www.ncbi.nlm.nih.gov/pubmed/29184422
http://dx.doi.org/10.2147/IDR.S146595