Cargando…
Quantitative phosphoproteomic analysis of acquired cancer drug resistance to pazopanib and dasatinib
Acquired drug resistance impacts the majority of patients being treated with tyrosine kinase inhibitors (TKIs) and remains a key challenge in modern anti-cancer therapy. The lack of clinically effective therapies to overcome resistance represents an unmet need. Understanding the signalling that driv...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673060/ https://www.ncbi.nlm.nih.gov/pubmed/28842319 http://dx.doi.org/10.1016/j.jprot.2017.08.015 |