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Quantitative phosphoproteomic analysis of acquired cancer drug resistance to pazopanib and dasatinib
Acquired drug resistance impacts the majority of patients being treated with tyrosine kinase inhibitors (TKIs) and remains a key challenge in modern anti-cancer therapy. The lack of clinically effective therapies to overcome resistance represents an unmet need. Understanding the signalling that driv...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673060/ https://www.ncbi.nlm.nih.gov/pubmed/28842319 http://dx.doi.org/10.1016/j.jprot.2017.08.015 |