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TRAIL deletion prevents liver inflammation but not adipose tissue inflammation during murine diet‐induced obesity

Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) and its cognate receptor(s) are up‐regulated in human and murine nonalcoholic steatohepatitis (NASH); however, the consequence of this enhanced expression on NASH pathogenesis remains unclear. TRAIL may either accentuate liver injury by...

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Detalles Bibliográficos
Autores principales: Hirsova, Petra, Weng, Peggy, Salim, Warda, Bronk, Steven F., Griffith, Thomas S., Ibrahim, Samar H., Gores, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673124/
https://www.ncbi.nlm.nih.gov/pubmed/29124251
http://dx.doi.org/10.1002/hep4.1069