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Radiotherapy and chemotherapy change vessel tree geometry and metastatic spread in a small cell lung cancer xenograft mouse tumor model

BACKGROUND: Tumor vasculature is critical for tumor growth, formation of distant metastases and efficiency of radio- and chemotherapy treatments. However, how the vasculature itself is affected during cancer treatment regarding to the metastatic behavior has not been thoroughly investigated. Therefo...

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Detalles Bibliográficos
Autores principales: Frenzel, Thorsten, Hoffmann, Bertin, Schmitz, Rüdiger, Bethge, Anja, Schumacher, Udo, Wedemann, Gero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673169/
https://www.ncbi.nlm.nih.gov/pubmed/29107953
http://dx.doi.org/10.1371/journal.pone.0187144