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Radiotherapy and chemotherapy change vessel tree geometry and metastatic spread in a small cell lung cancer xenograft mouse tumor model
BACKGROUND: Tumor vasculature is critical for tumor growth, formation of distant metastases and efficiency of radio- and chemotherapy treatments. However, how the vasculature itself is affected during cancer treatment regarding to the metastatic behavior has not been thoroughly investigated. Therefo...
Autores principales: | Frenzel, Thorsten, Hoffmann, Bertin, Schmitz, Rüdiger, Bethge, Anja, Schumacher, Udo, Wedemann, Gero |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673169/ https://www.ncbi.nlm.nih.gov/pubmed/29107953 http://dx.doi.org/10.1371/journal.pone.0187144 |
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