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Local application of an ibandronate/collagen sponge improves femoral fracture healing in ovariectomized rats

Non-union is a major clinical problem in the healing of fractures, especially in patients with osteoporosis. The systemic administration of drugs is time consuming and large doses are demanding and act slowly, whereas local release acts rapidly, increases the quality and quantity of the bone tissue....

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Detalles Bibliográficos
Autores principales: Guo, Jialiang, Zhang, Qi, Li, Jia, Liu, Yansong, Hou, Zhiyong, Chen, Wei, Jin, Lin, Tian, Ye, Ju, Linlin, Liu, Bo, Dong, Tianhua, Zhang, Fei, Zhang, Yingze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673204/
https://www.ncbi.nlm.nih.gov/pubmed/29108027
http://dx.doi.org/10.1371/journal.pone.0187683