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Synthetic host defense peptide IDR-1002 reduces inflammation in Pseudomonas aeruginosa lung infection

Pseudomonas aeruginosa is a frequent cause of lung infections, particularly in chronic infections in cystic fibrosis patients. However, treatment is challenging due to P. aeruginosa evasion of the host immune system and the rise of antibiotic resistant strains. Host defense peptides (HDPs) and synth...

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Detalles Bibliográficos
Autores principales: Wuerth, Kelli C., Falsafi, Reza, Hancock, Robert E. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673212/
https://www.ncbi.nlm.nih.gov/pubmed/29107983
http://dx.doi.org/10.1371/journal.pone.0187565