Rnr1, but not Rnr3, facilitates the sustained telomerase-dependent elongation of telomeres

Ribonucleotide reductase (RNR) provides the precursors for the generation of dNTPs, which are required for DNA synthesis and repair. Here, we investigated the function of the major RNR subunits Rnr1 and Rnr3 in telomere elongation in budding yeast. We show that Rnr1 is essential for the sustained el...

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Detalles Bibliográficos
Autores principales: Maicher, André, Gazy, Inbal, Sharma, Sushma, Marjavaara, Lisette, Grinberg, Gilad, Shemesh, Keren, Chabes, Andrei, Kupiec, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673236/
https://www.ncbi.nlm.nih.gov/pubmed/29069086
http://dx.doi.org/10.1371/journal.pgen.1007082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673236/
https://www.ncbi.nlm.nih.gov/pubmed/29069086
http://dx.doi.org/10.1371/journal.pgen.1007082

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