RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of α2 GABA(A) receptors

In developing brain neuronal migration, dendrite outgrowth and dendritic spine outgrowth are controlled by Cdc42, a small GTPase of the Rho family, and its activators. Cdc42 function in promoting actin polymerization is crucial for glutamatergic synapse regulation. Here, we focus on GABAergic synaps...

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Detalles Bibliográficos
Autores principales: de Groot, Claire, Floriou-Servou, Amalia, Tsai, Yuan-Chen, Früh, Simon, Kohler, Manuela, Parkin, Georgia, Schwerdel, Cornelia, Bosshard, Giovanna, Kaila, Kai, Fritschy, Jean-Marc, Tyagarajan, Shiva K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673238/
https://www.ncbi.nlm.nih.gov/pubmed/29069083
http://dx.doi.org/10.1371/journal.pgen.1007073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673238/
https://www.ncbi.nlm.nih.gov/pubmed/29069083
http://dx.doi.org/10.1371/journal.pgen.1007073

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