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RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of α2 GABA(A) receptors
In developing brain neuronal migration, dendrite outgrowth and dendritic spine outgrowth are controlled by Cdc42, a small GTPase of the Rho family, and its activators. Cdc42 function in promoting actin polymerization is crucial for glutamatergic synapse regulation. Here, we focus on GABAergic synaps...
Autores principales: | de Groot, Claire, Floriou-Servou, Amalia, Tsai, Yuan-Chen, Früh, Simon, Kohler, Manuela, Parkin, Georgia, Schwerdel, Cornelia, Bosshard, Giovanna, Kaila, Kai, Fritschy, Jean-Marc, Tyagarajan, Shiva K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673238/ https://www.ncbi.nlm.nih.gov/pubmed/29069083 http://dx.doi.org/10.1371/journal.pgen.1007073 |
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