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Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments

The actomyosin ring generates force to ingress the cytokinetic cleavage furrow in animal cells, yet its filament organization and the mechanism of contractility is not well understood. We quantified actin filament order in human cells using fluorescence polarization microscopy and found that cleavag...

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Detalles Bibliográficos
Autores principales: Spira, Felix, Cuylen-Haering, Sara, Mehta, Shalin, Samwer, Matthias, Reversat, Anne, Verma, Amitabh, Oldenbourg, Rudolf, Sixt, Michael, Gerlich, Daniel W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673306/
https://www.ncbi.nlm.nih.gov/pubmed/29106370
http://dx.doi.org/10.7554/eLife.30867