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Development of Novel Patient-Derived Xenografts from Breast Cancer Brain Metastases

Brain metastases are an increasing burden among breast cancer patients, particularly for those with HER2(+) and triple negative (TN) subtypes. Mechanistic insight into the pathophysiology of brain metastases and preclinical validation of therapies has relied almost exclusively on intracardiac inject...

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Detalles Bibliográficos
Autores principales: Contreras-Zárate, María J., Ormond, D. Ryan, Gillen, Austin E., Hanna, Colton, Day, Nicole L., Serkova, Natalie J., Jacobsen, Britta M., Edgerton, Susan M., Thor, Ann D., Borges, Virginia F., Lillehei, Kevin O., Graner, Michael W., Kabos, Peter, Cittelly, Diana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673842/
https://www.ncbi.nlm.nih.gov/pubmed/29164052
http://dx.doi.org/10.3389/fonc.2017.00252