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Development of Novel Patient-Derived Xenografts from Breast Cancer Brain Metastases
Brain metastases are an increasing burden among breast cancer patients, particularly for those with HER2(+) and triple negative (TN) subtypes. Mechanistic insight into the pathophysiology of brain metastases and preclinical validation of therapies has relied almost exclusively on intracardiac inject...
Autores principales: | Contreras-Zárate, María J., Ormond, D. Ryan, Gillen, Austin E., Hanna, Colton, Day, Nicole L., Serkova, Natalie J., Jacobsen, Britta M., Edgerton, Susan M., Thor, Ann D., Borges, Virginia F., Lillehei, Kevin O., Graner, Michael W., Kabos, Peter, Cittelly, Diana M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673842/ https://www.ncbi.nlm.nih.gov/pubmed/29164052 http://dx.doi.org/10.3389/fonc.2017.00252 |
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