Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability

Pancreatic acinar cell carcinoma (ACC) is an aggressive exocrine tumor with largely unknown biology. Here, to identify potential targets for personalized treatment, we perform integrative genome-wide and epigenome-wide analyses. The results show frequently aberrant DNA methylation, abundant chromoso...

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Detalles Bibliográficos
Autores principales: Jäkel, Cornelia, Bergmann, Frank, Toth, Reka, Assenov, Yassen, van der Duin, Daniel, Strobel, Oliver, Hank, Thomas, Klöppel, Günter, Dorrell, Craig, Grompe, Markus, Moss, Joshua, Dor, Yuval, Schirmacher, Peter, Plass, Christoph, Popanda, Odilia, Schmezer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673892/
https://www.ncbi.nlm.nih.gov/pubmed/29109526
http://dx.doi.org/10.1038/s41467-017-01118-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673892/
https://www.ncbi.nlm.nih.gov/pubmed/29109526
http://dx.doi.org/10.1038/s41467-017-01118-x

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